The film was released six years after Tj's World first premiered on Nickelodeon in 1999. The film was released in theaters on March 18, 2005 and received generally favorable reviews from critics and fans alike. The film was released on DVD on August 23, 2005.
On its opening weekend, the film grossed $33,461,560 being released in 3,312 theaters, leaving it #2 during the weekend behind The Ring Two. On its second weekend, it remained in its #2 spot for the weekend, grossing $18,367,290. The film grossed $187,431,005 worldwide, making the film a box office success.
The film was released on DVD on August 23, 2005, with widescreen and fullscreen versions of the film, and a featurette documenting the film's production. A Blu-Ray Disc edition of the film was released on May 17, 2011.
After the film's release, "Edit Your Friends" was made the theme song for the series, which previously had no theme song but had a very short opening sequence. The songs "Every Day Is Exactly The Same", "The National Anthem", "With Teeth", "Exploder", "Everything In Its Right Place", "Goof" and the instrumental version of "Edit Your Friends" do not appear in the film. "Edit Your Friends" and "Backdrifts" are played during the credits.